Neuropathology of hypoglycaemic brain injury

The Neuropathology and Neurobiology of Traumatic Brain Injury

The acute and long-term consequences of traumatic brain injury (TBI) have received increased attention in recent years. In this Review, we discuss the neuropathology and neural mechanisms associated with TBI, drawing on findings from sports-induced TBI in athletes, in whom acute TBI damages axons and elicits both regenerative and degenerative tissue responses in the brain and in whom repeated c...

Update of neuropathology and neurological recovery after traumatic brain injury.

This review focuses on the potential for traumatic brain injury to evoke both focal and diffuse changes within the brain parenchyma, while considering the cellular constituents involved and the subcellular perturbations that contribute to their dysfunction. New insight is provided on the pathobiology of traumatically induced cell body injury and diffuse axonal damage. The consequences of axonal...

Hypoxic-ischemic brain injury: pathophysiology, neuropathology and mechanisms.

Hypoxic-ischemic brain injury is a well known consequence of cardiac arrest. Variable injuries can occur with purely hypoxic or histotoxic insults such as asphyxiation and carbon monoxide poisoning. The injury may happen at the time of the insult, but there may also be continued damage after circulation and oxygenation are reestablished. The nature and extent of the damage appears to depend on ...

Update on mild traumatic brain injury: neuropathology and structural imaging.

The Neuropathology of Head Injury

Acute head injury Epidemiology In the United Kingdom more than 150,000 patients are admitted to hospital each year with an acute head injury. Of this group more than 80% are classified as having a mild head injury, as defined by the Glasgow Coma Scale (GCS). Approximately 1-2% of patients admitted to hospital after traumatic brain injury die as a consequence of their injuries with the majority ...